Question

خسارات جبران ناپذیر

- نبود اون خسارات جبران ناپذیری را به همراه داشت.

Answer 1

Her absence/departure caused an irreversible damage to... 

Answer 2

irreparable

irreparable damage, harm etc is so bad that it can never be repaired or made better
Extensive mining will cause irreparable damage to the area. (Webster)

irrecoverable

something that is irrecoverable is lost or has gone and you cannot get it back
irrecoverable loss of sight (Webster)

Or , in other ways:

e.g. Nothing can make up for his / her absence in the project. 

e.g. Our loss by / due to his / her absence (in the project / in here) cannot be compensated. / would not be compensable.

 

Answer 3

Irredeemable loss